Thrombosis Risk Assessment In The COVID-19 Era

Main Article Content

Joseph A Caprini

Abstract

The appearance of the coronavirus pandemic has prompted a renewed interest in thrombosis risk assessment, particularly since this disease is associated with a high risk of thrombotic events. It is known that the number one preventable cause of death in hospitalized patients including those having surgical procedures is fatal pulmonary emboli. There is also high-quality data that the use of anticoagulant drugs in the proper dose, and for the period of time shown to be efficacious, will prevent most fatal events. It is true that even with the use of the best anticoagulant regimes venous thromboembolic events (VTE) can still occur but are rarely fatal. We also realize that providing adequate anticoagulant prophylaxis for the entire period of risk is the key to preventing these deaths.  Thrombosis risk scoring identifies who's at risk for these emboli and guides physician choices for appropriate preventive measures.



Article Details

How to Cite
1.
Caprini JA. Thrombosis Risk Assessment In The COVID-19 Era. Health Sci J [Internet]. 2020Jun.23 [cited 2024May1];10(3):1-. Available from: https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1006
Section
EDITORIAL
Author Biography

Joseph A Caprini, NorthShore University HealthSystem, Evanston, Illinois, USA.

Senior Clinician Educator at the Pritzker School of Medicine at the University of Chicago. Emeritus physician at NorthShore University HealthSystem in Evanston, Illinois.

References

1. Tang N, Bai H, Chen X, Gong J, Li D, Sun Z. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020;18:1094-9. doi: 10.1111/jth.14817
2. Wakefield TW, McLafferty RB, Lohr JM, et al. Call to action to prevent venous thromboembolism. J Vasc Surg. 2009;49:1620-3. doi: 10.1016/j.jvs.2009.01.058
3. Haas S, Wolf H, Kakkar AK, Fareed J, Encke A. Prevention of fatal pulmonary embolism and mortality in surgical patients. A randomized double-blind comparison of LMWH with unfractionated heparin. Thromb Haemost. 2005;94(4):814-9. doi: 10.1160/th02-10-0189
4. Golemi I, Salazar Adum JP, Tafur A, Caprini J. Venous thromboembolism prophylaxis using the Caprini score. Dis Mon. 2019;65(8):249-98. doi: 10.1016/j.disamonth.2018.12.005
5. Fuentes HE, Paz LH, Al-Ogaili A, et al. Validation of a patient-completed Caprini Risk Score for venous thromboembolism risk assessment. TH Open. 2017;1(2):e106-e12. doi: 10.1055/s-0037-1607339
6. Klok FA, Kruip M, van der Meer NJM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020;191:145-7. doi: 10.1016/j.thromres.2020.04.013
7. Marston W, Labropoulos N, Caprini J, The COVID-19 Sub-Committee of the American Venous Forum. Considerations in prophylaxis and treatment of VTE in COVID-19 Patients [Internet]. East Dundee: American Venous Forum website;2020 Apr 17 [cited 2020 Jun 22]. Avaiable from: www.veinforum.org/wp-content/uploads/2020/04/COVID-19-White-Paper-04-17-2020-FINAL-1.pdf
8. Moores LK, Tritschler T, Brosnahan S, Carrier M, Collen JF, Doerschug K, et al. Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report. Chest. 2020:S0012-3692(20)31625-1 [Epub]. doi: 10.1016%2Fj.chest.2020.05.559
9. Helms J, Tacquard C, Severac F, et al. High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med. 2020;46(6):1089-98. doi: 10.1007%2Fs00134-020-06062-x
10. Arcelus JI, Monreal M, Caprini JA, et al. Clinical presentation and time-course of postoperative venous thromboembolism: Results from the RIETE Registry. Thromb Haemost. 2008;99(3):546-51. doi: 10.1160/th07-10-0611
11. Bikdeli B, Madhavan MV, Jimenez D, et al. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020;75(23):2950-73. doi: 10.1016/j.jacc.2020.04.031