Occurrence of tinnitus and peripheral sensory neuropathy in women during chemotherapy treatment of breast cancer

Main Article Content

Simone Yuriko Kameo
Ricardo Barbosa-Lima
https://orcid.org/0000-0001-5274-4800
Josilene Luciene Duarte
https://orcid.org/0000-0001-5177-1030
Bruno Ferreira Amorim
https://orcid.org/0000-0002-2581-2983
Glebson Moura Silva
https://orcid.org/0000-0002-4977-2787
Pabliane Matias Lordelo Marinho
Namie Okino Sawada
https://orcid.org/0000-0002-1874-3481

Abstract

Objective: To analyze the occurrence of tinnitus and peripheral sensory neuropathy in women during breast cancer chemotherapy. Methods: This is a retrospective analytical study with a quantitative approach, performed in medical records of an oncology outpatient service between February 2014 and February 2015, using the toxicities scores of Common Terminology Criteria for Adverse Events (CTCAE). Results: Considering 181 patients with breast cancer who met the inclusion criteria, 49.2% reported tinnitus at some point of the treatment, while 65.1% peripheral sensory neuropathy. In both conditions, the predominant severity score was grade 1, with frequencies of 23.8% and 33.1%, respectively. A significant, positive and weak correlation was observed between the severity of tinnitus and peripheral sensory neuropathy (ρ = 0.325 and p = 0.001), as well as very weak between the number of complete cycles of chemotherapy and tinnitus (ρ = 0.195 and p = 0.009) and neuropathy peripheral sensory (ρ = 0.237 and p = 0.002). Conclusions: Tinnitus and peripheral sensory neuropathy were frequent toxicities during chemotherapy treatment of breast cancer, and both manifested with low severity/functional impact in most participants.



Article Details

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1.
Kameo SY, Barbosa-Lima R, Duarte JL, Amorim BF, Silva GM, Marinho PML, et al. Occurrence of tinnitus and peripheral sensory neuropathy in women during chemotherapy treatment of breast cancer. HSJ [Internet]. 2021 Mar. 16 [cited 2024 Nov. 4];11(1):69-7. Available from: https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1089
Section
ORIGINAL ARTICLE
Author Biographies

Simone Yuriko Kameo, Department of Health Education, Federal University of Sergipe

Nurse. PhD in Nursing. Department of Health Education, Federal University of Sergipe, Lagarto, SE, Brazil.

Ricardo Barbosa-Lima, Department of Dentistry of Lagarto, Federal University of Sergipe.

Dental surgeon. Department of Dentistry of Lagarto, Federal University of Sergipe. Lagarto, SE, Brazil.

Josilene Luciene Duarte, Department of Speech Therapy of Lagarto, Federal University of Sergipe.

Speech therapist. PhD in Oral Biology. Department of Speech Therapy of Lagarto, Federal University of Sergipe. Lagarto, SE, Brazil.

Bruno Ferreira Amorim, Department of Medicine of Lagarto, Federal University of Sergipe.

Graduating in Medicine. Department of Medicine of Lagarto, Federal University of Sergipe. Lagarto, SE, Brazil.

Glebson Moura Silva, Department of Nursing of Lagarto, Federal University of Sergipe.

Nurse. PhD in Education. Department of Nursing of Lagarto, Federal University of Sergipe. Lagarto, SE, Brazil.

Pabliane Matias Lordelo Marinho, School of Nursing of Ribeirão Preto, University of São Paulo.

Nurse. PhD in Nursing. School of Nursing of Ribeirão Preto, University of São Paulo. Ribeirão Preto, SP, Brazil.

Namie Okino Sawada, School of Nursing, Federal University of Alfenas

Nurse. PhD in Nursing. School of Nursing, Federal University of Alfenas. Alfenas, MG, Brazil.

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