Cardiovascular disorders in patients with Zika Virus: integrative review
Main Article Content
Abstract
Objective: To describe the primary cardiovascular disorders manifested in patients infected with the zika virus and understand the pathophysiological process. Methods: This integrative literature review occurred in January 2021 through the PICO strategy, which answered the guiding question: “What are the main cardiovascular disorders manifested in patients infected with zika virus?” For this, a time interval of 5 years was defined, using the descriptors “Zika Virus”,“Heart” and “Cardiovascular Diseases” in English, Portuguese and Spanish. The contemplated databases were MEDLINE, LILACS, and BDENF. Results: There were a total of 77,872 articles, of which, after the exclusion and inclusion processes, it was summarized in eight articles included in this review. The main cardiovascular findings present were apical muscular ventricular septal defect and ostium secundum, in addition to atrial fibrillation and heart failure with reduced ejection fraction. Conclusions: Further studies with more robustness that clearly establish the mechanism of cellular tropism for cardiac muscle cells and involve the pathophysiological process of cardiac alterations more clearly and reliably are needed.
Article Details
Authors maintain copyright and grant the HSJ the right to first publication. From 2024, the publications wiil be licensed under Attribution 4.0 International , allowing their sharing, recognizing the authorship and initial publication in this journal.
Authors are authorized to assume additional contracts separately for the non-exclusive distribution of the version of the work published in this journal (e.g., publishing in an institutional repository or as a book chapter), with acknowledgment of authorship and initial publication in this journal.
Authors are encouraged to publish and distribute their work online (e.g., in institutional repositories or on their personal page) at any point after the editorial process.
Also, the AUTHOR is informed and consents that the HSJ can incorporate his article into existing or future scientific databases and indexers, under the conditions defined by the latter at all times, which will involve, at least, the possibility that the holders of these databases can perform the following actions on the article.
References
Wikan N, Smith DR. Zika virus: history of a newly emerging arbovirus. Lancet Infect Dis. 2016;16(7):e119-26. https://doi.org/10.1016/S1473-3099(16)30010-X DOI: https://doi.org/10.1016/S1473-3099(16)30010-X
Kuno G, Chang GJ. Full-length sequencing and genomic characterization of Bagaza, Kedougou, and Zika viruses. Arch Virol. 2007;152(4):687-96. https://doi.org/10.1007/s00705-006-0903-z DOI: https://doi.org/10.1007/s00705-006-0903-z
Brasil P, Pereira JP Jr, Moreira ME, Ribeiro Nogueira RM, Damasceno L, Wakimoto M, et al. Zika Virus Infection in Pregnant Women in Rio de Janeiro. N Engl J Med. 2016;375(24):2321-34. https://doi.org/10.1056/NEJMoa1602412 DOI: https://doi.org/10.1056/NEJMoa1602412
Gordon-Lipkin E, Peacock G. The spectrum of developmental disability with Zika exposure: what is known, what is unknown, and implications for clinicians. J Dev Behav Pediatr. 2019;40(5):387-95. https://doi.org/10.1097/DBP.0000000000000665 DOI: https://doi.org/10.1097/DBP.0000000000000665
Cao-Lormeau VM, Blake A, Mons S, Lastère S, Roche C, Vanhomwegen J, et al. Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet. 2016;387(10027):1531-9. https://doi.org/10.1016/S0140-6736(16)00562-6 DOI: https://doi.org/10.1016/S0140-6736(16)00562-6
Moore CA, Staples JE, Dobyns WB, Pessoa A, Ventura CV, Fonseca EB, et al. Characterizing the pattern of anomalies in Congenital Zika Syndrome for Pediatric Clinicians. JAMA Pediatr. 2017;171(3):288-95. https://doi.org/10.1001/jamapediatrics.2016.3982 DOI: https://doi.org/10.1001/jamapediatrics.2016.3982
Minhas AM, Nayab A, Iyer S, Narmeen M, Fatima K, Khan MS, et al. Association of Zika Virus with myocarditis, heart failure, and arrhythmias: a literature review. Cureus. 2017;9(6):e1399. https://doi.org/10.7759/cureus.1399 DOI: https://doi.org/10.7759/cureus.1399
Orofino DH, Passos SR, de Oliveira RV, Farias CV, Leite MF, Pone SM, et al. Cardiac findings in infants with in utero exposure to Zika virus- a cross sectional study. PLoS Negl Trop Dis. 2018;12(3):e0006362. https://doi.org/10.1371/journal.pntd.0006362 DOI: https://doi.org/10.1371/journal.pntd.0006362
Carta KG, Britto IJ, Meza Y, Morr I, Marques J, Flores VF, et al. Sex and gender differences in Zika myocarditis. J Am Coll Cardiol. 2019;73(9 Supp 1):719. https://doi.org/10.1016/S0735-1097(19)31327-0 DOI: https://doi.org/10.1016/S0735-1097(19)31327-0
Botelho LL, Cunha CC, Macedo M. O Método da revisão integrativa nos estudos organizacionais. Gestão e Sociedade. 2011;5(11):121-36. https://doi.org/10.21171/ges.v5i11.1220 DOI: https://doi.org/10.21171/ges.v5i11.1220
Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018,169(7):467-73. https://doi.org/10.7326/M18-0850 DOI: https://doi.org/10.7326/M18-0850
Brugnolli A, Cavada L, Saiani L. II sistema GRADE. Vol. 33, Assistenza Infermieristica e Ricerca. 2014. 924-926 p.
Abdalla LF, Santos JH, Barreto RT, Souza EM, D'Assunção FF, Borges MA, et al. Atrial fibrillation in a patient with Zika virus infection. Virol J. 2018;15:23. https://doi.org/10.1186/s12985-018-0938-2 DOI: https://doi.org/10.1186/s12985-018-0938-2
Angelidou A, Michael Z, Hotz A, Friedman K, Emani S, LaRovere K, et al. Is there more to Zika? Complex cardiac disease in a case of Congenital Zika Syndrome. Neonatol. 2018;113(2):177-82. https://doi.org/10.1159/000484656 DOI: https://doi.org/10.1159/000484656
Cavalcanti DD, Alves LV, Furtado GJ, Santos CC, Feitosa FG, Ribeiro MC, et al. Echocardiographic findings in infants with presumed congenital Zika syndrome: Retrospective case series study. PLoS One. 2017;12(4):e0175065. https://doi.org/10.1371/journal.pone.0175065 DOI: https://doi.org/10.1371/journal.pone.0175065
Orofino DH, Passos SR, Pone SM, Pone MV, Aguiar EB, Araújo IO, et al. 24-hour Holter findings in infants with in-utero exposure to the Zika virus: a series of cases. Rev Inst Med Trop São Paulo. 2020;62:e50. https://doi.org/10.1590/s1678-9946202062050 DOI: https://doi.org/10.1590/s1678-9946202062050
Rossi F, Josey B, Sayitoglu EC, Potens R, Sultu T, Duru AD, et al. Characterization of zika virus infection of human fetal cardiac mesenchymal stromal cells. PLoS One. 2020;15(9):e0239238. Erratum in: PLoS One. 2021;16(1):e0246112. https://doi.org/10.1371/journal.pone.0239238 DOI: https://doi.org/10.1371/journal.pone.0239238
Krittanawong C, Zhang H, Sun T. Cardiovascular complications after Zika virus infection. Int J Cardiol. 2016;221:859. https://doi.org/10.1016/j.ijcard.2016.06.293 DOI: https://doi.org/10.1016/j.ijcard.2016.06.293
Strange DP, Jiyarom B, Pourhabibi Zarandi N, Xie X, Baker C, Sadri-Ardekani H, et al. Axl promotes Zika Virus entry and modulates the antiviral state of human Sertoli cells. MBio. 2019;10(4):e01372-19. https://doi.org/10.1128/mBio.01372-19 DOI: https://doi.org/10.1128/mBio.01372-19
Lemke G. Biology of the TAM receptors. Cold Spring Harb Perspect Biol. 2013;5(11):a009076. https://doi.org/10.1101/cshperspect.a009076 DOI: https://doi.org/10.1101/cshperspect.a009076
Seferović PM, Polovina M, Bauersachs J, et al. Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2019;21(5):553-76. https://doi.org/10.1002/ejhf.1461 DOI: https://doi.org/10.1002/ejhf.1500