Cardiac autonomic activity, endothelial function and physical fitness in type 2 diabetic patients

Main Article Content

Cauê Padovani
https://orcid.org/
Regiane Maria da Costa Arruda
https://orcid.org/0000-0003-2775-0576
Shane Phillips
Luciana Maria Malosá Sampaio

Abstract

Objective: To investigate the association between cardiac autonomic activity, endothelial function, and physical fitness in patients with type 2 diabetes mellitus (T2DM). Methods: Twenty-seven patients with T2DM were studied, with a mean age of 57 ± 9 years and a mean disease duration of 7.4 ± 5 years. The assessment of physical fitness was performed using the Shuttle Walking Test (SWT), cardiac autonomic modulation by heart rate variability (HRV), and endothelial function was assessed by flow-mediated dilation (FMD) of the brachial artery through ultrasound imaging. Results: The main finding of this study was that some HRV indices (SDNN, RMSSD, and HF) were significantly correlated with endothelial function in individuals with T2DM, with R values between 0.51 and 0.57 (p < 0, 05), for all relationships. Additionally, an association was found between the distance covered in the SWT and the basal diameter of the brachial artery (R = 0.59; p = 0.01). Conclusion: Our data demonstrate that some HRV indices are associated with DMF, indicating an interaction between these two systems. Furthermore, our findings suggest a correlation between physical fitness and endothelial function in individuals with T2DM.



Article Details

How to Cite
1.
Padovani C, Arruda RM da C, Phillips S, Sampaio LMM. Cardiac autonomic activity, endothelial function and physical fitness in type 2 diabetic patients. HSJ [Internet]. 2022 Sep. 5 [cited 2024 Nov. 2];12(3):53-60. Available from: https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1279
Section
ORIGINAL ARTICLE
Author Biographies

Cauê Padovani, Nove de Julho University

PhD in Rehabilitation Sciences from the Nove de Julho University, Master in Rehabilitation Sciences from the University of São Paulo

Regiane Maria da Costa Arruda, Nove de Julho University

Master in Rehabilitation Sciences from Universidade Nove de Julho.

Shane Phillips, University of Illinois

Professor and Associate Head of the Department of Physical Therapy at the University of Illinois at Chicago.

Luciana Maria Malosá Sampaio, Nove de Julho University

Professor of the Postgraduate Program in Rehabilitation Sciences at Universidade Nove de Julho.

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