Identificação de casais sorodiscordantes, suas características clínicas, laboratoriais e vulnerabilidades de risco de transmissão do HIV no Nordeste do Brasil na era da profilaxia pré-exposição (PrEP)

Conteúdo do artigo principal

Maíra Gomes Monteiro
https://orcid.org/0000-0002-0040-6567
Adriana Farrant Braz
Kledoaldo Lima
http://orcid.org/0000-0003-2505-7516
Heloísa Ramos Lacerda

Resumo

Objetivo: Avaliar a frequência de casais sorodiscordantes para o HIV candidatos à profilaxia pré-exposição (PrPE) e o conhecimento sobre medidas comportamentais para reduzir a transmissão do vírus. Métodos: A pesquisa foi realizada no nordeste do Brasil, de fevereiro de 2016 a março de 2017. Noventa indivíduos HIV positivos (Índice) e seus parceiros HIV negativos (n = 17) foram submetidos a questionários epidemiológicos, clínicos e laboratoriais e a testes laboratoriais rápidos para sífilis, hepatite B e C. Resultados: Altas frequências de co-infecção com HIV-sífilis (34,4%) e HIV-HBV (3,3%) foram detectadas nos indivíduos HIV-positivos. Três novos casos de HIV foram detectados em parceiros. A maioria dos participantes dos dois grupos (85,6%, Índice; 94,1%, Parceiros) possuía um excelente conhecimento sobre a transmissão do HIV, embora nove parceiros soronegativos com alto risco de infecção pelo HIV tenham sido identificados (53%). Os indivíduos HIV positivos apresentaram alta frequência de co-infecção por sífilis e 10% deles não usaram antirretroviral por opção pessoal. Conclusões: A adoção da PrPE e outras medidas preventivas para prevenir a transmissão do HIV em casais sorodiscordantes devem ser estudadas e avaliadas.



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1.
Monteiro MG, Farrant Braz A, Lima K, Ramos Lacerda H. Identificação de casais sorodiscordantes, suas características clínicas, laboratoriais e vulnerabilidades de risco de transmissão do HIV no Nordeste do Brasil na era da profilaxia pré-exposição (PrEP). HSJ [Internet]. 9º de maio de 2020 [citado 3º de julho de 2024];10(2):13-9. Disponível em: https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/931
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ARTIGO ORIGINAL

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