Research integrity in times of pandemic

Main Article Content

Seleno Glauber de Jesus-Silva
https://orcid.org/0000-0002-2205-1090
Ana Carolina Peçanha Antonio
https://orcid.org/0000-0001-6146-1247

Abstract

In 1994, Douglas Graham Altman, one of the greatest statisticians of all time, wrote "We need less research, better research, and research done for good reasons". Twenty-seven years ago, Altman pointed out that the system favored unscientific behavior and that "bad science" was easy to publish, highlighting the financial implications of this amount of poorly designed research, with erroneous statistical methods, unrepresentative samples, or fraud. The covid-19 pandemic has once again put clinical research in check. The pressure for urgent responses was unprecedented. Knowledge of the origin of the virus, the transmission dynamics, the pathophysiology of the disease, efficient pharmacological and non-pharmacological measures would be counted in lives - and economies, and in governments.



Article Details

How to Cite
1.
Jesus-Silva SG de, Antonio ACP. Research integrity in times of pandemic. HSJ [Internet]. 2021 Sep. 30 [cited 2024 Nov. 22];11(3):3-5. Available from: https://portalrcs.hcitajuba.org.br/index.php/rcsfmit_zero/article/view/1220
Section
EDITORIAL
Author Biographies

Seleno Glauber de Jesus-Silva, Itajuba Clinics Hospital

Graduated in Medicine at the Federal University of Pará (2001). Specialist in Vascular Surgery (MEC and SBACV / AMB), in Angioradiology and Endovascular Surgery (MEC) and in Interventional Radiology and Angioradiology (SoBRICE / CBR / AMB). General Coordinator of Medical Residency and Internships at Itajuba Clinics Hospital (HCI). Medical Coordinator of the Surgical Center and CME of HCI. Master of Science from the Federal University of São Paulo. PhD student in Unifesp/EPM. Scientific Editor of Revista Ciências em Saúde - ISSN 2236-3785 Has experience in Vascular Surgery, Interventional Radiology and Endovascular Surgery.

Ana Carolina Peçanha Antonio, Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul

Graduated in Medicine from the Federal University of Rio Grande do Sul (2006), residency in Internal Medicine from the Hospital de Clinicas de Porto Alegre (2007-2010), residency in Intensive Medicine from the Hospital Moinhos de Vento (2010-2012) and PhD in Pulmonary Sciences from the Federal University of Rio Grande do Sul (2016). Works at the Adult ICU and at the Nutrology Service of the Hospital de Clinicas de Porto Alegre, also acting as a member of the Health Technology Assessment Center of this institution. Performs the role of clinical management of the ICUs of Hospital Independência, which belongs to the Rede de Saúde Divina Providência.

References

Altman DG. The scandal of poor medical research. BMJ. 1994;308:283. https://doi.org/10.1136/bmj.308.6924.283 PMid:8124111 PMCid:PMC2539276 DOI: https://doi.org/10.1136/bmj.308.6924.283

Takagi H. COVID‐19 pandemic and medical publication. Eur J Clin Invest. 2020;50(11):e13394. https://doi.org/10.1111/eci.13394 PMid:32886801 DOI: https://doi.org/10.1111/eci.13394

Bagdasarian N, Cross GB, Fisher D. Rapid publications risk the integrity of science in the era of COVID-19. BMC Med. 2020;18(1):192. https://doi.org/10.1186/s12916-020-01650-6 PMid:32586327 PMCid:PMC7315694 DOI: https://doi.org/10.1186/s12916-020-01650-6

Elgendy IY, Nimri N, Barakat AF, Ibrahim J, Mandrola J, Foy A. A systematic bias assessment of top-cited full-length original clinical investigations related to COVID-19. Eur J Intern Med. 2021;86:104-6. https://doi.org/10.1016/j.ejim.2021.01.018 PMid:33541829 PMCid:PMC7826014 DOI: https://doi.org/10.1016/j.ejim.2021.01.018

Watch R. Retracted coronavirus (COVID-19) papers [Internet]. 2021 [cited 2021 Sep 28]. Available from: https://retractionwatch.com/retracted-coronavirus-covid-19-papers/

Anderson C, Nugent K, Peterson C. Academic Journal Retractions and the COVID-19 Pandemic. J Prim Care Community Heal. 2021;12:215013272110155. https://doi.org/10.1177/21501327211015592 PMid:33949228 PMCid:PMC8114243 DOI: https://doi.org/10.1177/21501327211015592

Dadalto L, Royo MM, Costa BS. Bioética e integridade científica nas pesquisas clínicas sobre covid-19. Revista Bioética. 2020;28(3):418-25. https://doi.org/10.1590/1983-80422020283402 DOI: https://doi.org/10.1590/1983-80422020283402

Alves CPL, Segundo JDB, Costa GG, Pereira-Cenci T, Lima KC, Demarco FF, et al. How a few poorly designed COVID-19 studies may have contributed to misinformation in Brazil: the case for evidence-based communication of science. BMJ Open Sci. 2021;5(1):e100202. https://doi.org/10.1136/bmjos-2021-100202 DOI: https://doi.org/10.1136/bmjos-2021-100202

Oreskes N. Why Bad Science Is Sometimes More Appealing Than Good Science [Internet]. 2021 [cited 2021 Sep 29]. Available from: https://www.scientificamerican.com/article/why-bad-science-is-sometimes-more-appealing-than-good-science/

Allen RM. When peril responds to plague: predatory journal engagement with COVID-19. Libr Hi Tech. 2021;39(3):746-60. https://doi.org/10.1108/LHT-01-2021-0011 DOI: https://doi.org/10.1108/LHT-01-2021-0011

Dinis-Oliveira RJ. COVID-19 research: pandemic versus "paperdemic", integrity, values and risks of the "speed science." Forensic Sci Res. 2020;5(2):1-14. https://doi.org/10.1080/20961790.2020.1767754 PMid:32939434 PMCid:PMC7476615 DOI: https://doi.org/10.1080/20961790.2020.1767754

Calster BV, Wynants L, Riley RD, Smeden M van, Collins GS. Methodology over metrics: Current scientific standards are a disservice to patients and society. J Clin Epidemiol. 2021; S0895-4356(21)00170-0. https://doi.org/10.1016/j.jclinepi.2021.05.018 PMid:34077797 DOI: https://doi.org/10.1016/j.jclinepi.2021.05.018

Mehra MR, Ruschitzka F, Patel AN. Retraction-Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis. Lancet. 2020;395(10240):1820. https://doi.org/10.1016/S0140-6736(20)31324-6 DOI: https://doi.org/10.1016/S0140-6736(20)31324-6

Neto JG, Antonio ACP, Tessler L. Integridade em pesquisa clínica: o caso da proxalutamida [Internet]. 2021 [cited 2021 Sep 29]. Available from: http://revistaquestaodeciencia.com.br/artigo/2021/08/10/integridade-em-pesquisa-clinica-o-caso-da-proxalutamida

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